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Chengru Zhu Phones & Addresses

  • Little Rock, AR
  • 9 Heather Hill Rd, Catonsville, MD 21228 (410) 247-2148 (410) 247-2299
  • 833 Hollins St, Baltimore, MD 21201 (410) 230-0275
  • Albuquerque, NM
  • Lovettsville, VA
  • Newhall, CA

Work

Company: Mdhmh laboratories administration Jun 2007 Position: Division chief

Education

School / High School: University of Montreal School of Medicine- Montral, QC 1996 Specialities: Ph. D. in Microbiology & Immunology

Skills

Bacterial identification by biochemical ... • molecular characterization of virulence ... • cell culture • protein toxin purification and detection • hemagglutination inhibition • novel assay development • cell culture • monoclonal antibody development • immunohistochemistry • ELISA • ELISPOT • immunofluorescence microscopy • tissue sectioning and staining • Gene cloning and expression • sequence analysis • site-directed and mutagenesis • gene expression in eukaryotic and prokar... • PCR • RT-PCR • real time PCR • protein expression • purification and characterization • protein-protein interaction • immunoprecipitation • Western blot. Development of bacterial v... • construction of mucosal delivery vaccine... • vaccine safety and protection studies. T... • including transcutaneous immunization • Development of DNA vaccines for bacteria... • molecular • biochemical • and serological methods for the isolation • detection • identification • and confirmation of foodborne bacterial ...

Public records

Vehicle Records

Chengru Zhu

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Address:
9 Heather Hl Rd, Catonsville, MD 21228
VIN:
1HGCM56827A092679
Make:
HONDA
Model:
ACCORD
Year:
2007

Resumes

Resumes

Chengru Zhu Photo 1

Chengru Zhu Catonsville, MD

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Work:
MDHMH Laboratories Administration

Jun 2007 to 2000
Division Chief

University of Yangzhou

2002 to 2000
Adjunct Professor

University of New Mexico School of Medicine
Albuquerque, NM
Nov 2005 to Jun 2007
Research Assistant Professor

University of Maryland School of Medicine
Baltimore, MD
Apr 1999 to Oct 2005
Assistant professor, Instructor, Postdoc

Institute Armand-Frappier and VIDO
Laval, QC
May 1996 to Apr 1999
Postdoctoral fellow

Diagnostic laboratory
Yangzhou, CN
Aug 1982 to Aug 1991
Lab scientist, then Lab lead

Education:
University of Montreal School of Medicine
Montral, QC
1996
Ph. D. in Microbiology & Immunology

University of Yangzhou (Former Jiangsu Agri. College)
1982
M. Sc. in Veterinary Microbiology

University of Yangzhou (Former Jiangsu Agri. College)
1980
B.V.Sc. in Veterinary Science

Skills:
Bacterial identification by biochemical and molecular methods, molecular characterization of virulence factors, cell culture, protein toxin purification and detection, hemagglutination inhibition, novel assay development, cell culture, monoclonal antibody development, immunohistochemistry, ELISA, ELISPOT, immunofluorescence microscopy, tissue sectioning and staining, Gene cloning and expression, sequence analysis, site-directed and mutagenesis, gene expression in eukaryotic and prokaryotic cells, PCR, RT-PCR, real time PCR, protein expression, purification and characterization, protein-protein interaction, immunoprecipitation, Western blot. Development of bacterial vaccines for enteric pathogens, construction of mucosal delivery vaccine vectors, vaccine safety and protection studies. Target protein expression optimized by modification of promoter sequences for aerobic/anaerobic or constitutive/inducible expression. Development and utilization of novel vaccination strategies, including transcutaneous immunization, Development of DNA vaccines for bacterial and viral infections. Development of vaccine candidates by codon optimization of the genes of interests and synthetic gene. Laboratory animal skills. Possesses knowledge and skills essential to and applicable in microbiological examination of environmental samples by cultural, molecular, biochemical, and serological methods for the isolation, detection, identification, and confirmation of foodborne bacterial pathogens;

Publications

Us Patents

Live Attenuated Bacterial Vaccine To Reduce Or Inhibit Carriage And Shedding Of Enterohemorrhagic Escherichia Coli In Cattle

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US Patent:
20080286310, Nov 20, 2008
Filed:
Oct 26, 2005
Appl. No.:
11/666251
Inventors:
Chengru Zhu - Albuquerque NM, US
Edgar Boedeker - Placitas NM, US
Assignee:
UNIVERSITY OF MARYLAND BALTIMORE - Baltimore MD
International Classification:
A61K 39/108
C12N 1/20
C12N 15/09
US Classification:
4242571, 4352528, 435440
Abstract:
The invention provides live, attenuated enterohemorrhagic (EHEC) bacteria in which the Shiga toxin coding sequences are deleted to abolish Shiga toxin production and one or more of the nucleotide sequences for the bacterial adhesin protein intimin, the locus of enterocyte effacement encoded regulator, and the translocated intimin receptor are mutated to inactivate the activity of the encoded protein(s). This live, attenuated bacteria is used in a vaccine for reducing or inhibiting carriage and shedding of EHEC in cattle.
Chengru Zhu from Little Rock, AR, age ~66 Get Report