Chengru Zhu

MDHMH Laboratories Administration

Jun 2007 to 2000
Division Chief
University of Yangzhou

2002 to 2000
Adjunct Professor
University of New Mexico School of Medicine
Albuquerque, NM
Nov 2005 to Jun 2007
Research Assistant Professor
University of Maryland School of Medicine
Baltimore, MD
Apr 1999 to Oct 2005
Assistant professor, Instructor, Postdoc
Institute Armand-Frappier and VIDO
Laval, QC
May 1996 to Apr 1999
Postdoctoral fellow
Diagnostic laboratory
Yangzhou, CN
Aug 1982 to Aug 1991
Lab scientist, then Lab lead

University of Montreal School of Medicine
Montral, QC
1996
Ph. D. in Microbiology & Immunology
University of Yangzhou (Former Jiangsu Agri. College)
1982
M. Sc. in Veterinary Microbiology
University of Yangzhou (Former Jiangsu Agri. College)
1980
B.V.Sc. in Veterinary Science

Bacterial identification by biochemical and molecular methods, molecular characterization of virulence factors, cell culture, protein toxin purification and detection, hemagglutination inhibition, novel assay development, cell culture, monoclonal antibody development, immunohistochemistry, ELISA, ELISPOT, immunofluorescence microscopy, tissue sectioning and staining, Gene cloning and expression, sequence analysis, site-directed and mutagenesis, gene expression in eukaryotic and prokaryotic cells, PCR, RT-PCR, real time PCR, protein expression, purification and characterization, protein-protein interaction, immunoprecipitation, Western blot. Development of bacterial vaccines for enteric pathogens, construction of mucosal delivery vaccine vectors, vaccine safety and protection studies. Target protein expression optimized by modification of promoter sequences for aerobic/anaerobic or constitutive/inducible expression. Development and utilization of novel vaccination strategies, including transcutaneous immunization, Development of DNA vaccines for bacterial and viral infections. Development of vaccine candidates by codon optimization of the genes of interests and synthetic gene. Laboratory animal skills. Possesses knowledge and skills essential to and applicable in microbiological examination of environmental samples by cultural, molecular, biochemical, and serological methods for the isolation, detection, identification, and confirmation of foodborne bacterial pathogens;