Anthony J. Musoke - Kampala,
Vish Nene - Cambridge,
Keith Iams - Pittsburgh PA
Vinand M. Nantulya - Mbale,
International Laboratory for Research on Animal Diseases - Nairobi
This invention relates to the development of a vaccine against Theileria parva, which is a protozoan parasite infecting cattle in Africa. The invention specifically relates to the use of the 67 kDa glycoprotein from the surface of the T. parva sporozoite as an immunogen for inducing immunoprotection against T. parva in bovine species. This 67 kDa antigen is produced using recombinant genetics. Plasmids containing nucleic acid segments encoding the antigen, host cells containing the nucleic acid segments and recombinant methods for producing the antigen are part of this invention.