Nikolaos Robakis - Leonia NJ,
Philippe Marambaud - New York NY,
Anastasios Georgakopoulos - New York NY,
Mount Sinai School of Medicine of New York University - New York NY
514 2, 514 14, 435 23, 530326
The present invention provides polypeptides and peptides derived from cadherin. The polypeptides and peptides are useful in a method of inhibiting amyloid deposition and a method of inhibiting tumor metastasis. A method of determining susceptibility to Alzheimer's disease and a method of screening for agents that modify cadherin processing are also provided.